Angioedema is a swelling that is similar to hives, but the swelling is under the skin instead of on the surface.
Hives are often called welts. They are a surface swelling. It is possible to have angioedema without hives.
Angioneurotic edema; Welts
Causes, incidence, and risk factors
Angioedema may be caused by an allergic reaction. During the reaction, histamine and other chemicals are released into the bloodstream. The body releases histamine when the immune system detects a foreign substance called an allergen.
In most cases, the cause of angioedema is never found.
The health care provider will look at your skin and ask you if you have been exposed to any irritating substances. A physical exam might reveal abnormal sounds (stridor) when you breathe in if your throat is affected.
Wasserman SI. Approach to the person with allergic or immunologic disease. In: Goldman L, Schafer AI, eds. Cecil Medicine. 24th ed. Philadelphia, Pa: Saunders Elsevier;2011:chap 257.
David C. Dugdale, III., MD, Professor of Medicine, Division of General Medicine, Department of Medicine, University of Washington School of Medicine; and Stuart I. Henochowicz, MD, FACP, Associate Clinical Professor of Medicine, Division of Allergy, Immunology, and Rheumatology, Georgetown University Medical School. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M. Health Solutions, Ebix, Inc.