Amniocentesis removes a small amount of fluid from the sac that surrounds the baby in the womb (uterus). It is usually done in a doctor's office or medical center. You do not need to stay in the hospital.
You will probably have a pregnancy ultrasound first. This helps your health care provider find out exactly where the baby is in your womb.
Numbing medicine is then rubbed onto part of your belly. Sometimes, the medicine is given through a shot in the skin on the belly area.
The health care provider inserts a long, thin needle through your belly and into the womb. A small amount of fluid is removed from the sac surrounding the baby.
How to prepare for the test
Your bladder must be full for the ultrasound.
Before the test, blood may be taken to determine your blood type and Rh factor. You may get a shot of medicine called RhoGAM if you are Rh negative.
How the test will feel
If you get a shot of numbing medicine, you may feel a sharp, stinging sensation for a few seconds.
Some women feel a sharp pain for a few seconds when the needle enters the sac surrounding the baby.
Some women feel pressure in the lower belly area when the fluid is removed. After the procedure, you may have some minor cramping.
Why the test is performed
Amniocentesis can be used to diagnose many different gene and chromosome problems in the baby, including:
There may be alternatives to the amniocentesis. Discuss these other tests with your health care provider.
Simpson JL, Otaño L. Prenatal genetic diagnosis. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2007:chap 7.
Druzin ML, Smith JF Jr, Gabbe SG, Reed KL. Antepartum fetal evaluation. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, PA: Elsevier Churchill Livingstone; 2007:chap 11.
Cunningham FG, Leveno KJ, Bloom SL, et al. Prenatal diagnosis and fetal therapy. In: Cunningham FG, Leveno KL, Bloom SL, et al, eds. Williams Obstetrics. 23rd ed. New York, NY: McGraw-Hill; 2010:chap 13.
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Bellevue, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.