Most miscarriages are caused by chromosome problems that make it impossible for the baby to develop. Usually, these problems are unrelated to the mother or father's genes.
Other possible causes for miscarriage include:
Drug and alcohol abuse
Exposure to environmental toxins
Physical problems with the mother's reproductive organs
Problem with the body's immune response
Serious body-wide ( systemic) diseases in the mother (such as uncontrolled diabetes)
It is estimated that up to half of all fertilized eggs die and are lost (aborted) spontaneously, usually before the woman knows she is pregnant. Among those women who know they are pregnant, the miscarriage rate is about 15-20%. Most miscarriages occur during the first 7 weeks of pregnancy. The rate of miscarriage drops after the baby's heart beat is detected.
The risk for miscarriage is higher in women:
Older age, with increases beginning by 30, becoming greater between 35 and 40, and highest after 40
Who have had previous miscarriages
Possible symptoms include:
Low back pain or abdominal pain that is dull, sharp, or cramping
Tissue or clot-like material that passes from the vagina
Vaginal bleeding, with or without abdominal cramps
Signs and tests
During a pelvic exam, your health care provider may see the cervix has opened (dilated) or thinned out (effacement).
Abdominal or vaginal ultrasound may be done to check the baby's development, heart beat, and amount of bleeding.
When a miscarriage occurs, the tissue passed from the vagina should be examined to determine if it was a normal placenta or a hydatidiform mole. It is also important to determine whether any pregnancy tissue remains in the uterus.
If the pregnancy tissue does not naturally exit the body, the woman may be closely watched for up to 2 weeks. Surgery (D and C) or medication (such as misoprostol) may be needed to remove the remaining contents from the womb.
After treatment, the woman usually resumes her normal menstrual cycle within 4 - 6 weeks. Any further vaginal bleeding should be carefully monitored. It is often possible to become pregnant immediately. However, it is recommended that women wait one normal menstrual cycle before trying to become pregnant again.
An infected abortion may occur if any tissue from the placenta or fetus remains in the uterus after the miscarriage. Symptoms of an infection include fever, vaginal bleeding that does not stop, cramping, and a foul-smelling vaginal discharge. Infections can be serious and require immediate medical attention.
Complications of a complete miscarriage are rare. However, many mothers and their partners feel very sad. Seemingly helpful advice like “you can try again,” or “it was for the best” can make it harder for mothers and fathers to recover because their sadness has been denied.
Women who lose a baby after 20 weeks of pregnancy receive different medical care. This is called premature delivery or fetal demise and requires immediate medical attention.
Calling your health care provider
Call your health care provider if vaginal bleeding with or without cramping occurs during pregnancy.
Call your health care provider if you are pregnant and notice tissue or clot-like material passed vaginally (any such material should be collected and brought in for examination).
Early, comprehensive prenatal care is the best prevention available for all complications of pregnancy.
Many miscarriages that are caused by body-wide (systemic) diseases can be prevented by detecting and treating the disease before pregnancy occurs.
Miscarriages are less likely if you receive early, comprehensive prenatal care and avoid environmental hazards (such as x-rays, drugs and alcohol, high levels of caffeine, and infectious diseases).
When a mother's body is having difficulty sustaining a pregnancy, signs (such as slight vaginal bleeding) may occur. This means there is a possibility of miscarriage, but it does not mean one will definitely occur. A pregnant woman who develops any signs or symptoms of threatened miscarriage should contact her prenatal provider immediately.
Simpson JL, Jauniaux ERM. Pregnancy loss. In: Gabbe SG, Niebyl JR, Simpson JL, eds. Obstetrics: Normal and Problem Pregnancies. 5th ed. Philadelphia, Pa: Elsevier Churchill Livingstone; 2007:chap 24.
Laurino MY, Bennett RL, Saraiya DS, et al. Genetic evaluation and counseling of couples with recurrent miscarriage: Recommendations of the National Society of Genetic Counselors. J Genet Couns. June 2005;14(3).
Linda J. Vorvick, MD, Medical Director, MEDEX Northwest Division of Physician Assistant Studies, University of Washington, School of Medicine; Susan Storck, MD, FACOG, Chief, Eastside Department of Obstetrics and Gynecology, Group Health Cooperative of Puget Sound, Redmond, Washington; Clinical Teaching Faculty, Department of Obstetrics and Gynecology, University of Washington School of Medicine. Also reviewed by David Zieve, MD, MHA, Medical Director, A.D.A.M., Inc.